The Board of Trustees has been able to fund an important project on the risk of pre-term birth after treatment for cervical pre-cancer. Dr Maria Kyrgiou will lead the research in our laboratories at the IRDB in Hammersmith.
Cervical intra-epithelial neoplasia (CIN) is a precancerous disease of the cervix that is treated surgically with the removal of a cone-shaped part of the cervix. In England alone 23,800 women underwent this surgery in 2012. However, this technique doubles the risk of having a pre-term birth. The research team aims to understand if this increased risk is caused by the surgery itself or whether the immune defences of these women is compromised by the HPV infection (that causes CIN) or does the kind of bacteria in the birth canal differ as a result of the HPV infection and increase the risk of premature birth?