Our Work

Pre-term birth after cervical pre-cancer treatment

The Board of Trustees has been able to fund an important project on the risk of pre-term birth after treatment for cervical pre-cancer. Dr Maria Kyrgiou will lead the research in our laboratories at the IRDB in Hammersmith. Cervical intra-epithelial neoplasia (CIN) is a precancerous disease of the cervix that is treated surgically with the removal of...

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Fetal Programming

We now realise that our long term health depends on an interaction between our genes and our environment, and also that the environment of the womb is highly important in having long-term effects on a child’s wellbeing later. This phenomenon is known as fetal programming. Our research has shown that if the mother is stressed...

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PCOS

Polycystic Ovary Syndrome (PCOS) Polycystic Ovary Syndrome (PCOS) affects more than 5% of women of reproductive age and has a major impact both on fertility and on long-term health. It results in irregular menstruation, is the main reason for ovulation-related infertility and, because of its associated metabolic abnormalities, carries a high risk of developing diabetes....

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Microbiome studies

Professor Phil Bennett and colleagues are undertaking studies to understand the contribution of the vaginal microbiome to preterm labour and delivery. Preterm birth, which is defined as births before 37 weeks of gestation and occurs in some 10% of pregnancies, is a leading cause of neonatal mortality and morbidity. Evidence suggests that although there can...

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Recurrent Miscarriage

Recurrent miscarriage is a prevalent disorder that affects 1-2% of couples. In addition to the physical trauma and psychological stress, miscarriages are also associated with a variety of complications in a subsequent ongoing pregnancy, including preterm delivery, low birth weight and physical handicap. Chromosomal errors in the implanting embryo are a common finding, although more...

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Diseases of pregnant women

Obstetric cholestasis Maternal research focuses on obstetric cholestasis (OC), a serious problem in pregnancy which affects about one in 150 pregnancies or about 4,500 women a year in the UK. These women develop severe itching and sometimes jaundice. More importantly, the condition is associated with preterm birth and is also believed to be an important...

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Stem Cells

Stem cell research has the potential to impact not just one disease, but several. According to the research teams studying these diseases; diabetes, cancer, cardiovascular disease, Alzheimer's, Parkinson's, autoimmune disease, burn victims, blood diseases, leukemia, and spinal injuries could all benefit from stem cell research. All of us are made up of cells. They are...

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