Dear Professor Winston,

I am 43 years old, and unfortunately I find myself still single.  I am considering whether to have a child, trying to use my own eggs.  I have had a number of tests done:  AMH, LH, FSH.

I am aware of the low success rates at my age and as I am single I would need donor sperm. I was wondering if you could give me your thoughts on whether to try IUI, IVF, or just accept that I’ve left it too late and start the grieving process?  I do feel a need to at least try in order to get closure rather than not knowing.

I would be very grateful for your thoughts and thank you so much for offering this service.



Dear A.,

I can’t answer this because I don’t know you.  This kind of decision is so personal and depends on so many issues in your life and previous experience as well as future plans, that I think it very presumptuous for me to try.

As you say, you are aware of the low chance of success at your age with an evens chance of a miscarriage if you do get pregnant, and about 3% chance of a live birth on average. There’s approximately 100 : 1 chance of a baby with a chromosome abnormality.  Normally, I would argue that natural sexual activity its as good our better than IVF. But IUI and donor insemination are probably least good options.

Sorry not to be more use

Robert Winston

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